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I found the following bit of information within a supplement of a dermatology series aimed at skin and aging. I've posted the link elsewhere in another thread. As someone who has quite a bit of damage to my arms and hands as well as my face, I found it to be an attractive alternative to just suffering or paying tons of money for cosmetic treatments that may not treat the underlying cause. Has anyone used this topical?
"TREATING WIDESPREAD NON-FACIAL PHOTODAMAGE
For widespread non-facial photodamage, I always feel like I'm stuck between a rock and a hard place. For example, I dislike freezing numerous actinic keratoses (AKs) on a patient's lower legs. If I freeze enough to eliminate the lesions, then there's a high risk that the patient may experience ulceration and scarring. However, if I limit my treatment so that I don't put my patients through that ulceration and scarring process, I don't really effectively get rid of the lesions. At that point, I'm basically performing a sub-therapeutic freeze. Because of this treatment dilemma, I've almost completely stopped freezing AK lesions on the lower legs and also do little freezing on lesions in the chest area.
I've found, however, that 0.5% 5-fluorouracil works wonderfully for non-facial photodamage, which is an off-label use of this drug. I've successfully used it on the arms, hands, chest, lower legs and tops of the feet. Because the effects of 0.5% 5-fluorouracil seem to be somewhat diminished when you use it on non-facial areas, I have patients use it for 2 to 4 weeks, depending on the results they experience. "
5-fluorouracil = efudex, for those who may have used it.
I happen to have a tube of that I am using for Seborrheic keratoses on my back and sides of my torso right now Actually I had read that somewhere and talked my Derm into letting me try that. She had told me my insurance would not cover her zapping all those nasty spots that were popping up all over. She said it may or may not work for that. Some are lighter and smoother so far. But they are tougher and more stubborn than AK's
But I think it would be worth a shot using it for the AK's. I just might give it a shot on my arms instead of RA for months and months, with iffy results. Winter would be a good time, you could keep it covered, because you can bet it will have nasty red areas to deal with where they are.
There are some very good responses on this thread. However, about 80% of the prior responses (which I had to delete) were all SPAMMERS; 'comment spam' where people say something JUST TO drop a link to something they are selling. Unfortunately, this topic is a magnet for comment/link spam. So to maintain the integrity of it, now that it's been cleaned out of spammers, I need to lock it so more don't fly in here.
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