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which ingredients go or do NOT go together?

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which ingredients go or do NOT go together?

Postby hyeonjlee » Wed Feb 11, 2009 8:06 pm

Can we collectively share our knowledge on which ingredients are compatible with each other and which ones are NOT?

Well known facts first:

*** Copper Peptide and Vitamine C do NOT go together. Need to be applied at least 6 hours apart

*** Glucosimine and Niacinamide (Vitamine B3) are very synergistic

*** Given that various off the shelf products have B3, B5, and C (vitamines), I assume at the minimum they are NOT canceling each other's effectiveness

How about some other ingredients? Please add your insight/knowledge.

Does anyone know if Alpha Arbutin (good for hyperpigmentation problem) is compatible with above ingredients?
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Postby kylesmom9 » Mon Apr 27, 2009 10:15 am

Hi Hyeonjlee,

Did you ever start using the alpha arbutin? I just ordered some, and wondered what your experience has been. My intention is to mix it with the niacinamide/NAG and use at night. I am using licorice root right now, but not long enough to tell if it will yield results.

In the literature and some products I see that 3% is common.

TIA :)
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cps and renova

Postby yassie » Fri Jul 17, 2009 5:10 pm

i've been using copper peptides and Renova for a month and my face feels sensitive and itchy-should I slow down?
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Postby kylesmom9 » Sat Jul 18, 2009 6:49 am

Hi Yassie,

This thread is more about mixing your own formulations...not whether one can use products at the same time. The skincare board is probably a better place to post your question. It might be overlooked here. :)

I wish I could give you an answer...I use retin a but not copper peptides.
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Postby LLucy » Wed Aug 05, 2009 6:44 pm

Hyaluronic acid has the property of thickening a product.

While DMAE has the property of liquidating a gel, cream it is introduced into.

Something to consider when you want a product of a certain consistency.
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Re: which ingredients go or do NOT go together?

Postby clean » Mon Feb 01, 2010 3:00 pm

A good rule of thumb is to go by pH of the unbuffered solution. If your desired concentration will have a low pH unbuffered when mixed with water, do not mix it with a product that has a much higher pH unbuffered when mixed with water. Generally the substance will be most effective unbuffered.

All the B-vitamins should be at or around neutral.

Ascorbic acid is acidic. But the C derivatives might be ok at neutral pHs.

Do not mix ascorbic with B vitamins. They should be separate topicals. Wait a half hour or so before layering, or use one in the AM and one in the PM.

If you are not sure, look it up or ask here.

Sometimes there are additional constraints. We only know what has been studied, and some of these combinations have not been tested. So less is sometimes more. If you want lots of different actives it's safest to alternate use from day to day rather than put too many in the same formula. Just because there is a product out there that does make these combos that does not mean it will work. It's probably ineffectual but most people would not know that.
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